increase in alveolar/alveoli dead space?

The Danish authors of the 1917 paper were August Krogh and Johannes Lindhard (Fig. At the time, Haldane was a Fellow of New College, Oxford, and was well-known, not only for developing new methods of gas and blood analysis and for his researches in respiratory physiology but also for his success in solving a range of practical problems arising in clinical medicine, in coal mines and from the Royal Navy’s concerns for the survival of submariners and divers. 1A) and he was also senior author with JC Meakins and JG Priestley of the 1918/1919 paper. The author of the 1915 paper was John Scott Haldane (Fig.

The importance of the ratio, VA/QC, in pulmonary gas exchange did not appear in this paper de novo but emerged in two papers, published by physiologists in 19, concerned with the volume of the respiratory dead space. The concept was first suggested in a paper published in the 1918/1919 volume of The Journal of Physiology to account for the crippling breathlessness suffered by the soldiers who had survived gas attacks in the First World War. Large differences in the ratio of alveolar ventilation to alveolar capillary blood flow, VA/QC, in different regions of the lungs have been recognised as a principal cause of hypoxaemia in respiratory disease since the 1950s. The Physiological Society’s blue plaquesĪlveolar ventilation-perfusion ratios and pulmonary gas exchange: 100 years since recognition A debate about physiological measurement provides insight into a practical problemĭepartment of Bioengineering, Imperial College London, UKĬC Michel, Department of Bioengineering, Imperial College London, UK.The use of animals in educating the next generation of life science researchers.Sport & Exercise Science Education report.The Future of Interdisciplinary Research Beyond REF 2021.Scotland at the Heart of Meeting Global Challenges.Physiology and Basic Research Funding in Ireland.A National Post-Pandemic Resilience Programme.Supporting the development of public health guidance for long COVID.Translating Knowledge and Research into Impact.Advice for attending your first meeting.Early Career Life Scientists’ Symposium.Michael J Rennie Oral Communication Prize.The Journal of Physiology Early Investigator Prize.Experimental Physiology Inaugural Review Prize.Experimental Physiology Mid-Career Researcher Prize.Experimental Physiology Early Career Author Prize.The Otto Hutter Physiology Teaching Prize.The Journal of Physiology’s Virtual Journal Club.Human, Environmental & Exercise Physiology.Regenerating the Cardiovascular System: Mending Broken Hearts and Beyond

Increase in alveolar/alveoli dead space?